- Title
- Melanoma: An immunotherapy journey from bench to bedside
- Creator
- Navani, Vishal; Graves, Moria C.; Mandaliya, Hiren; Hong, Martin; van der Westhuizen, Andre; Martin, Jennifer; Bowden, Nikola A.
- Publisher Link
- http://dx.doi.org/10.1007/978-3-030-96376-7_2
- Publisher
- Springer Nature
- Resource Type
- book chapter
- Date
- 2022
- Description
- Melanoma gave science a window into the role immune evasion plays in the development of malignancy. The entire spectrum of immune focused anti-cancer therapies has been subjected to clinical trials in this disease, with limited success until the immune checkpoint blockade era. That revolution launched first in melanoma, heralded a landscape change throughout cancer that continues to reverberate today.
- Subject
- immune checkpoint; immunotherapy; melanoma; PD-1; PD-L1; CTLA-4; immunotherapy resistnace; immunotherapy response
- Identifier
- http://hdl.handle.net/1959.13/1468930
- Identifier
- uon:48125
- Identifier
- ISBN:9783030963767
- Language
- eng
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